Yaroslavl, Yaroslavl, Russian Federation
Yaroslavl, Yaroslavl, Russian Federation
The article examines the reduction of N (2,4 dinitrophenyl)morpholine in acidic medium by tin (II) chloride. Under these conditions there is a formation of a mixture of products of reduction, chlorination and heterocyclisation reactions. The authors developed a method for the preparation of condensed 3,4 dihydro-1H-benzo[4,5]imidazo[2,1-c][1,4]oxazines by reduction of (2-nitro-4-R-phenyl)morpholine into 5-R-2-piperidin-1-ylanilines followed by oxidative heterocyclisation with supramuravic acid.
N-(2-nitro-4-R-phenyl)morpholines, 3,4-dihydro-1H-benzo[4,5]imidazo[2,1-c][1,4]oxazines, reductive heterocyclisation, oxidative heterocyclisation
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