сотрудник
Ярославль, Ярославская область, Россия
студент
Ярославль, Ярославская область, Россия
На основе реакции взаимодействия 4-бром-5-нитрофталонитрила и первичных гетериламинов разработан метод синтеза не описанных в литературе орто-дикарбонитрилов, содержащих гетероциклические системы ряда индазола, хинолина, бензотиазола, тетрагидрохинолина.
нуклеофильное замещение, замещённые орто-дикарбонитрилы, индазол, хинолин, бензотиазол, тетрагидрохинолин, 4-бром-5-нитрофталонитрил
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2. Abramov I.G., Dorogov M.V., Smirnov A.V., Ivanovskii S.A., Abramova M.B., Plachtinsky V.V. The differing reactivity of the bromo and nitro groups in 4-bromo-5-nitrophthalonitrile towards nucleophilic attack. Mendeleev Commun. 2000. V. 2. P. 78. DOIhttps://doi.org/10.1070/MC2000v010n02ABEH001147.
3. Chirkova Z.V., Filimonov S.I., Abramov I.G. Synthesis of Functional Derivatives of Benzofuran-5,6-dicarboxylic Acids. Russian Journal of General Chemistry. 2019. V. 89. Issue 6. P. 1307-1309. DOI: 10.1134/ S1070363219060276/
4. Filimonov S.I., Chirkova Zh.V., Abramov I.G., Firgang S.I., Stashina G.A., Suponitsky K.Yu. Synthesis of Novel Substituted 4-Hydroxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-6,7-dicarbonitriles. Heterocycles. 2011. V. 83, N 4. Р. 755-763. DOI:https://doi.org/10.3987/COM-10-12128.
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7. Berezin D.B., Kustov A.V., Krestyaninov M.A., Batov D.V., Kukushkina N.V., Shukhto O.V The behavior of monocationic chlorin in water and aqueous solutions of non-ionic surfactant Tween 80 and potassium iodide. J. Molec. Liquids. 2019. V. 283. P. 532-536. DOI:https://doi.org/10.1016/j.molliq.2019.03.091
8. Mikhailova A.I., Znoiko S.A., Maizlish V.E., Shaposhnikov G.P, Abramov l.G., Abramova M.B. Nucleophilic Substitution of 4-Bromo-5-nitrophthalodinitrile: XVII. Synthesis and Properties of Bifunctionally Substituted Metal Phthalocyanines with Aryloxy and Nitro Groups. Russian Journal of General Chemistry. 2018. V. 88. Issue 7. P. 1425-1429. DOI:https://doi.org/10.1134/S1070363218040205.
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10. Chirkova Z.V., Kabanova М.V., Filimonov S.I., Abramov I.G., Petzer A., Hitge R., Petzer J.P., Suponitsky K.Y. Optimization of pyrrolo[3,4-f]indole-5,7-dione and indole-5,6-dicarbonitrile derivatives as inhibitors of monoamine oxidase. Drug Development Research. 2019. V. 80. Issue 7. P. 970-980. DOI:https://doi.org/10.1002/ddr.21576.
11. Chirkova Zh.V, Kabanova M.V., Filimonov S.I., Abramov I.G., Petzer A., Petzer J.P., Suponitsky K.Yu. An evaluation of synthetic indole derivatives as inhibitors of monoamine oxides. Bioorganic and Medicinal Chemistry Letters. 2016. V. 26 (9). P. 2214-2219. DOI:https://doi.org/10.1016/j.bmcl.2016.03.060.
12. Berezin D.B., Makarov V.V., Znoyko V.E., Mayzlish, Kustov A.V. Aggregation water soluble octaanionicphthalocyanines behavior and their S.A. photoinactivation antimicrobial effect in vitro. Mend. Commun, 2020. V. 30. N 5. P. 621-623. DOI:https://doi.org/10.1016/j.mencom.2020.09.023.
13. Caterino M., D'Aria F., Kustov A.V., Belykh D.V., Khudyaeva I.S., Starseva O.M., Berezin D.B., Pylina Y.I., Usacheva T.R., Amato J., Giancola C. Selective binding of a bioactive porphyrin-based photosensitizer to the G-quadruplex from the KRAS oncogene promoter. Intern. J. Biol. Macromolecules. 2020. V. 145. P. 244-251. DOI:https://doi.org/10.1016/j.ijbiomac.2019.12.152.
14. Filimonov S.I., Chirkova Zh.V., Abramov I.G., Firgang S.I., Stashina G.A., Suponitsky K.Yu. Synthesis of 2-oxo- and 2-thioxo-5-(benzofuran-2-yl)-tetrahydropyrimidines. Mendeleev Commun. 2011. V. 21. N 6. P. 332-333. DOI:https://doi.org/10.1016/j.mencom.2011.01.019.
15. Chirkova Zh.V., Filimonov S.I., Abramov I.G., Firgang S.I., Stashina G.A., Strelenko Yuri A., Khakimov D.V., Pivina T.S., Samet A.V., Suponitsky K.Yu. Base-induced transformations of ortho-nitrobenzylketones: intramolecular displacement of nitro group versus nitro-nitrite rearrangement. Tetrahedron. 2012. N 30. V. 68 Р. 5991–5997. DOI:https://doi.org/10.1016/j.tet.2012.05.034
16. Chirkova Zh.V., Kabanova M.V., Sharunov V.S., Danilova A.S., Abramov I.G., Filimonov S.I., Luferenko D.V., Soloviev M.E. New Nitrogen-Containing Five-Membered Heterocyclic ortho - Dicarbonitriles for Preparation of Macroheterocycles. Macroheterocycles. 2014. Vol. 7 (3), P. 296-301. DOI:https://doi.org/10.6060/mhcl40378c.
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