![Selective modification of tetrahydrochromeno[2,3-d]pyrimidin-2-ones](/upload/12631c5e396938a702bdd516ae8c4208/issues/cover/bdac7b872820fbffe311a9b1ab65ea2c.png)
Ярославль, Ярославская область, Россия
Ярославль, Ярославская область, Россия
с 01.01.2023 по настоящее время
Ярославский государственный технический университет
с 01.01.2018 по 01.01.2023
Ярославль, Ярославская область, Россия
аспирант
Ярославль, Ярославская область, Россия
студент
Ярославль, Ярославская область, Россия
The paper presents the results of the synthesis and characterisation of seven new tetrahydrochromeno[2,3-d]pyrimidin-2-ones derivatives obtained by selective modification of the hydroxyl group at the C-8 position. The authors successfully used alkylation and acetylation reactions to introduce substituents into the molecule. This resulted in a series of new heterocyclic compounds with yields up to 94 %. The authors characterised the obtained compounds by NMR spectroscopy (¹H and ¹³C) and mass spectrometry.
tetrahydrochromeno[2,3-d]pyrimidin-2-ones, methyl iodide, acetic anhydride, alkylation, acylation
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